Cell cycle regulation of p34cdc2 kinase activity in Physarum polycephalum
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چکیده
منابع مشابه
Cell cycle regulation of p34kinase activity in Physarum polycephalum
The regulation of the mitotic histone HI kinase activity has been analyzed during the naturally synchronous cell cycle of Physanun polycephalum plasmodia. The universal binding property of the pl3 Schizosaccharomyces pombe gene product was used to precipitate and assay the cdc2 histone HI kinase activity. The kinase activity peaks at the beginning of metaphase and its decline, which requires pr...
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A key component of Cdc2/Cdk2-activating kinase (CAK) is p40MO15, a protein kinase subunit that phosphorylates the T161/T160 residues of p34cdc2/p33cdk2. The level and activity of p40MO15 were essentially constant during cleavage of fertilised Xenopus eggs and in growing mouse 3T3 cells, but serum starvation of these cells reduced both the level and activity of p40MO15. Although the level and ac...
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Sodium-n-butyrate affects the length of the mitotic cycle of Physarum polycephalum. Application during S- or early G2-period results in a delay of the subsequent mitosis, whereas application later in the cycle has no delaying effect. Interestingly, the second mitotic cycle after application is considerably shortened when butyrate has been administered during S- or early G2-period of the precedi...
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ژورنال
عنوان ژورنال: Journal of Cell Science
سال: 1990
ISSN: 1477-9137,0021-9533
DOI: 10.1242/jcs.96.4.683